Anzi Heji (AZHJ) has been used to deal with anticardiolipin antibody– (ACA-) optimistic pregnant ladies liable to spontaneous abortion for a few years. The intention of this research was to research the protecting mechanism of AZHJ in a mouse mannequin of ACA-positive being pregnant liable to spontaneous abortion utilizing label-free quantitative proteomics. Mice have been divided into three teams: regular pregnant mice (management group), ACA-positive pregnant mice administered regular saline (mannequin group), and ACA-positive pregnant mice administered AZHJ (AZHJ group).
The mannequin was established by injecting βproteomic and bioinformatic analyses. The degrees of IL-6, IL-10, ACA, and TNF-α within the serum and placentas of the mice have been measured by enzyme-linked immunosorbent assays (ELISAs). Proteomic information have been validated by western blot evaluation. The irregular serum and placental ranges of IL-6, ACA, and TNF-α within the mannequin group have been reversed by AZHJ. There have been 39 upregulated and 10 downregulated DEPs within the AZHJ group relative to the mannequin group.
Bioinformatic evaluation revealed that the DEPs have been primarily concerned in nucleic acid binding, sign conduction, and posttranslational modification. The placental ranges of T-cell immunoglobulin mucin 3 (Tim-3) and Toll-like receptor 4 (TLR4) expression and AKT phosphorylation within the three teams have been per the proteomic findings. Tim-3/AKT signaling is concerned in maternal-fetal immune tolerance, whereas TLR4 is related to inflammatory responses. Collectively, these outcomes point out that AZHJ might exert its protecting impact in ACA-positive pregnant mice by regulating the maternal-fetal immune tolerance and inflammatory response.
Merchandise have been subjected to liquid chromatography-tandem mass spectrometry (LC-MS/MS) evaluation and searched towards a UniProt Homo sapiens database. Relative protein abundance was decided for every pattern. Primarily based on proteomics outcomes, lumican was measured by enzyme-linked immunosorbent assay (ELISA) and Western blot evaluation was carried out for interleukin-1 receptor antagonist (IL-1Ra) and tissue inhibitor of matrix metalloproteinase-2 (TIMP-2). Cell viability was decided by calcein AM (stay) and ethidium homodimer (lifeless) staining and confocal microscopy.
Proteomic evaluation revealed 919 proteins within the 9 merchandise. Proteins have been primarily collagens, keratin, and albumin. Lumican, a small leucine-rich proteoglycan (SLRP) was present in all samples. Western blot evaluation for IL-1Ra and TIMP-2 indicated presence of each proteins, with nonspecific antibody binding additionally current in all samples. No stay cells have been recognized in any product.
Schwann Cell Stimulation of Pancreatic Most cancers Cells: A Proteomic Evaluation
Schwann cells (SCs), the glial element of peripheral nerves, have been recognized as promoters of pancreatic most cancers (PC) development, however the molecular mechanisms are unclear. Within the current research, we aimed to establish proteins launched by SCs that might stimulate PC progress and invasion. Proteomic evaluation of human major SC secretome was carried out utilizing liquid chromatography-tandem mass spectrometry, and a complete of 13,796 distinctive peptides comparable to 1,470 particular person proteins have been recognized.
Metabolic and cell-cell adhesion pathways confirmed the best ranges of enrichment, a discovering in step with the supportive function of SCs in peripheral nerves. We recognized seven SC-secreted proteins that have been validated by western blot. The involvement of those SC-secreted proteins was additional demonstrated by utilizing blocking antibodies. PC cell proliferation and invasion induced by SC-conditioned media have been decreased utilizing blocking antibodies towards the matrix metalloproteinase-2, cathepsin D, plasminogen activator inhibitor-1, and galectin-1.
Blocking antibodies towards the proteoglycan biglycan, galectin-Three binding protein, and tissue inhibitor of metalloproteinases-2 decreased solely the proliferation however not the invasion of PC cells. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment have been performed utilizing the Database for Annotation, Visualization, and Built-in Discovery. The elevated expression of phosphorylated ARPC2 discovered within the PBMCs of our sufferers, and its affiliation with derangement of F-actin filaments, would possibly recommend that proteins regulating actin dynamics in immune cells might be concerned within the mechanism of CAMR of kidney grafts.
Collectively, this research delineates the secretome of human SCs and identifies proteins that may stimulate PC cell progress and invasion and subsequently represent potential therapeutic targets. Altogether, 503 lysine succinylation websites in 303 proteins have been recognized. Lactate dehydrogenase A (LDHA), the important thing enzyme in Warburg impact, was discovered extremely succinylated at Ok222 in GC. Intriguingly, this modification didn’t have an effect on LDHA ubiquitination, however decreased the binding of ubiquitinated LDHA to SQSTM1, thereby lowering its lysosomal degradation.
Altered Phosphorylation of Cytoskeleton Proteins in Peripheral Blood Mononuclear Cells Characterizes Power Antibody-Mediated Rejection in Kidney Transplantation
Power antibody-mediated rejection (CAMR) is the key reason for kidney transplant failure. The molecular mechanisms underlying this occasion are nonetheless poorly outlined and this lack of understanding deeply influences the potential therapeutic methods. The intention of our research was to investigate the phosphoproteome of peripheral blood mononuclear cells (PBMCs), to establish mobile signaling networks differentially activated in CAMR. Phosphoproteins remoted from PBMCs of biopsy confirmed CAMR, kidney transplant recipients with regular graft operate and histology and wholesome immunocompetent people, have been investigated by proteomic evaluation.
 MagSi-proteomics C18 |
|
MD01009 |
AMSBIO |
2 mL |
EUR 391.2 |
 MagSi-proteomics C4 |
|
MD01014 |
AMSBIO |
2 mL |
EUR 391.2 |
 MagSi-proteomics C8 |
|
MD01015 |
AMSBIO |
2 mL |
EUR 391.2 |
MagSi-proteomics C4 |
|
MD02014 |
AMSBIO |
10 mL |
EUR 1332 |
MagSi-proteomics C8 |
|
MD02015 |
AMSBIO |
10 mL |
EUR 1332 |
MagSi-proteomics C18 |
|
MD03009 |
AMSBIO |
10 mL |
EUR 1332 |
MagSi-proteomics C4 |
|
MD03014 |
AMSBIO |
100 mL |
EUR 7260 |
MagSi-proteomics C8 |
|
MD03015 |
AMSBIO |
100 mL |
EUR 7260 |
MagSi-proteomics C18 |
|
MD04009 |
AMSBIO |
100 mL |
EUR 7260 |
 ELISA Kit) Human Osteonectin (ON) ELISA Kit |
|
DLR-ON-Hu-48T |
DL Develop |
48T |
EUR 574.8 |
|
|
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Osteonectin (ON) in samples from serum, plasma, tissue homogenates or other biological fluids. |
Human Osteonectin (ON) ELISA Kit |
|
DLR-ON-Hu-96T |
DL Develop |
96T |
EUR 745.2 |
|
|
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Osteonectin (ON) in samples from serum, plasma, tissue homogenates or other biological fluids. |
 ELISA Kit) Mouse Osteonectin (ON) ELISA Kit |
|
DLR-ON-Mu-48T |
DL Develop |
48T |
EUR 586.8 |
|
|
|
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Osteonectin (ON) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Mouse Osteonectin (ON) ELISA Kit |
|
DLR-ON-Mu-96T |
DL Develop |
96T |
EUR 762 |
|
|
|
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Osteonectin (ON) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
 ELISA Kit) Rat Osteonectin (ON) ELISA Kit |
|
DLR-ON-Ra-48T |
DL Develop |
48T |
EUR 609.6 |
|
|
|
Description: A sandwich quantitative ELISA assay kit for detection of Rat Osteonectin (ON) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Rat Osteonectin (ON) ELISA Kit |
|
DLR-ON-Ra-96T |
DL Develop |
96T |
EUR 793.2 |
|
|
|
Description: A sandwich quantitative ELISA assay kit for detection of Rat Osteonectin (ON) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Human Osteonectin (ON) ELISA Kit |
|
RD-ON-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 573.6 |
Human Osteonectin (ON) ELISA Kit |
|
RD-ON-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 794.4 |
Mouse Osteonectin (ON) ELISA Kit |
|
RD-ON-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 586.8 |
Mouse Osteonectin (ON) ELISA Kit |
|
RD-ON-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 812.4 |
Rat Osteonectin (ON) ELISA Kit |
|
RD-ON-Ra-48Tests |
Reddot Biotech |
48 Tests |
EUR 613.2 |
Rat Osteonectin (ON) ELISA Kit |
|
RD-ON-Ra-96Tests |
Reddot Biotech |
96 Tests |
EUR 850.8 |
Human Osteonectin (ON) ELISA Kit |
|
RDR-ON-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 600 |
Human Osteonectin (ON) ELISA Kit |
|
RDR-ON-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 830.4 |
Mouse Osteonectin (ON) ELISA Kit |
|
RDR-ON-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 613.2 |
Mouse Osteonectin (ON) ELISA Kit |
|
RDR-ON-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 850.8 |
Rat Osteonectin (ON) ELISA Kit |
|
RDR-ON-Ra-48Tests |
Reddot Biotech |
48 Tests |
EUR 640.8 |
Rat Osteonectin (ON) ELISA Kit |
|
RDR-ON-Ra-96Tests |
Reddot Biotech |
96 Tests |
EUR 890.4 |
-Biotin) LC-LC(+)-Biotin |
|
abx184150-5g |
Abbexa |
5 g |
EUR 1195.2 |
|
|
 AGAROSE MS, PCR SCREENING, MOLECULAR BIOLOGY GRADE, 100G/UNIT, 10 UNITS PER CASE |
|
AGR-MS-1001 |
CORNING |
1/pk |
EUR 2445.6 |
|
Description: Bioscience Mol Bio; Agarose |
 Biotin-LC-LC-NHS |
|
2346-1000 |
Biovision |
|
EUR 2010 |
Biotin-LC-LC-NHS |
|
2346-250 |
Biovision |
|
EUR 705.6 |
Biotin-LC-LC-NHS |
|
2346-5000 |
Biovision |
|
Ask for price |
 AlbuVoid Binding Buffer AVBB |
|
AVBB-1000 |
Biotech Support Group |
1000 mL |
EUR 547.2 |
|
Description: Albuvoid™ Buffer |
 AlbuVoid Buffer Kit - 1000 |
|
AVBK-1000 |
Biotech Support Group |
1000 mL |
EUR 1399.2 |
|
Description: Albuvoid™ Buffer |
 AlbuVoid Elution Buffer AVEB |
|
AVEB-1000 |
Biotech Support Group |
1000 mL |
EUR 547.2 |
|
Description: Albuvoid™ Buffer |
 AlbuVoid Wash Buffer AVWB |
|
AVWB-1000 |
Biotech Support Group |
1000 mL |
EUR 547.2 |
|
Description: Albuvoid™ Buffer |
 Trypsin, Recombinant, Proteomics grade |
|
P1228-1000 |
Biovision |
|
EUR 235.2 |
Trypsin, Recombinant, Proteomics grade |
|
P1228-10000 |
Biovision |
|
EUR 1468.8 |
Trypsin, Recombinant, Proteomics grade |
|
P1228-5000 |
Biovision |
|
EUR 738 |
 (3 biotin/BSA)) Biotinylated Bovine Serum Albumin (Biotin-LC-BSA) (3 biotin/BSA) |
|
7097-25 |
Biovision |
|
EUR 266.4 |
Biotinylated Bovine Serum Albumin (Biotin-LC-BSA) (3 biotin/BSA) |
|
7097-5 |
Biovision |
|
EUR 138 |
 (5 biotin/BSA)) Biotinylated Bovine Serum Albumin (Biotin-LC-BSA) (5 biotin/BSA) |
|
7098-25 |
Biovision |
|
EUR 279.6 |
Biotinylated Bovine Serum Albumin (Biotin-LC-BSA) (5 biotin/BSA) |
|
7098-5 |
Biovision |
|
EUR 144 |
 (12 biotin/BSA)) Biotinylated Bovine Serum Albumin (Biotin-LC-BSA) (12 biotin/BSA) |
|
7099-25 |
Biovision |
|
EUR 292.8 |
Biotinylated Bovine Serum Albumin (Biotin-LC-BSA) (12 biotin/BSA) |
|
7099-5 |
Biovision |
|
EUR 157.2 |
 101Bio Protein Solubilization Reagent for MS |
|
P5W11 |
101Bio |
- |
Ask for price |
 MS 275 |
|
abx076834-1mg |
Abbexa |
1 mg |
EUR 376.8 |
|
|
) LC-Protein Kinase G Substrate; LC-Gsubtide (Biotin) |
|
20-abx265657 |
Abbexa |
-
EUR 560.40
-
EUR 927.60
-
EUR 427.20
|
|
|
|
 Bangs Lab Bead Solution |
|
SOLN1-1000 |
Bangs Laboratories |
1000 ML |
EUR 186.07 |
|
Description: Bangs Lab Bead Solution is ready-to-use solution and is suitable for dilution and/or storage of plain, dyed, or functionalized polymer microspheres |
Bangs Lab Bead Solution |
|
SOLN1-2000 |
Bangs Laboratories |
2000 ML |
EUR 255.24 |
|
Description: Bangs Lab Bead Solution is ready-to-use solution and is suitable for dilution and/or storage of plain, dyed, or functionalized polymer microspheres |
Bangs Lab Bead Solution |
|
SOLN1-500 |
Bangs Laboratories |
500 ML |
EUR 118.21 |
|
Description: Bangs Lab Bead Solution is ready-to-use solution and is suitable for dilution and/or storage of plain, dyed, or functionalized polymer microspheres |
 NHS-LC-Biotin |
|
A8004-100 |
ApexBio |
100 mg |
EUR 142.8 |
|
Description: NHS-LC-biotin (succinimidyl-6-(biotinamindo)hexanoate), also known as NHS-X-biotin is a derivative of D-biotin, a amine-reactive biotinylation agent, that contains a spacer arm off the valeric acid side chain of D-biotin with an NHS ester group at its end. |
NHS-LC-Biotin |
|
A8004-1000 |
ApexBio |
1 g |
EUR 657.6 |
|
Description: NHS-LC-biotin (succinimidyl-6-(biotinamindo)hexanoate), also known as NHS-X-biotin is a derivative of D-biotin, a amine-reactive biotinylation agent, that contains a spacer arm off the valeric acid side chain of D-biotin with an NHS ester group at its end. |
 Iodoacetyl-LC-Biotin |
|
A8009-100 |
ApexBio |
100 mg |
EUR 316.8 |
|
Description: Iodoacetyl-LC-Biotin (N-iodoacetyl-N-biotinylhexylenediamine), a sulfhydryl-reactive biotinylation agent, is a water-insoluble reagent that requires the dissolution of suitable solvents, including dimethyl sulfoxide (DMSO) and dimethylformamide (DMF). |
 CD49f LC antibody |
|
70R-49925 |
Fitzgerald |
100 ul |
EUR 292.8 |
|
Description: Purified Polyclonal CD49f LC antibody |
 CD49e LC antibody |
|
70R-49932 |
Fitzgerald |
100 ul |
EUR 292.8 |
|
Description: Purified Polyclonal CD49e LC antibody |
 Kininogen LC antibody |
|
23031-100ul |
SAB |
100ul |
EUR 468 |
 CD224 LC Antibody |
|
20-abx121054 |
Abbexa |
-
EUR 360.00
-
EUR 526.80
-
EUR 226.80
|
|
|
|
 Enteropeptidase LC Antibody |
|
20-abx121089 |
Abbexa |
-
EUR 360.00
-
EUR 526.80
-
EUR 226.80
|
|
|
|
 MASP1 LC Antibody |
|
20-abx121154 |
Abbexa |
-
EUR 360.00
-
EUR 526.80
-
EUR 226.80
|
|
|
|
 Myeloperoxidase LC Antibody |
|
20-abx121172 |
Abbexa |
-
EUR 360.00
-
EUR 526.80
-
EUR 226.80
|
|
|
|
 CD49e LC Antibody |
|
20-abx009097 |
Abbexa |
-
EUR 360.00
-
EUR 526.80
-
EUR 226.80
|
|
|
|
 CD49f LC Antibody |
|
20-abx009102 |
Abbexa |
-
EUR 360.00
-
EUR 526.80
-
EUR 226.80
|
|
|
|
-Biotin) sulfo-LC-(+)-Biotin |
|
20-abx185570 |
Abbexa |
-
EUR 444.00
-
EUR 1513.20
-
EUR 693.60
|
|
|
|
-Biotin hydrazide) LC-(+)-Biotin hydrazide |
|
abx185659-1g |
Abbexa |
1 g |
EUR 777.6 |
|
|
-Biotin) LC-NHS-(+)-Biotin |
|
20-abx185861 |
Abbexa |
|
|
|
|
) ELISA kit for Human MS (Melatonin Sulfate) |
|
E-EL-H1726 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 640.8 |
|
|
|
Description: A competitive ELISA kit for quantitative measurement of Human MS (Melatonin Sulfate) in samples from Serum, Plasma, Cell supernatant |
) ELISA kit for Human Melatonin sulfate (MS) |
|
KTE61523-48T |
Abbkine |
48T |
EUR 424.8 |
|
Description: Quantitative sandwich ELISA for measuring Human Melatonin sulfate (MS) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Melatonin sulfate (MS) |
|
KTE61523-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2702.4 |
|
Description: Quantitative sandwich ELISA for measuring Human Melatonin sulfate (MS) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Melatonin sulfate (MS) |
|
KTE61523-96T |
Abbkine |
96T |
EUR 686.4 |
|
Description: Quantitative sandwich ELISA for measuring Human Melatonin sulfate (MS) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
) ELISA kit for Human ON (Osteonectin) |
|
E-EL-H1351 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 640.8 |
|
|
|
Description: A sandwich ELISA kit for quantitative measurement of Human ON (Osteonectin) in samples from Serum, Plasma, Cell supernatant |
) ELISA kit for Mouse ON (Osteonectin) |
|
E-EL-M0867 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 640.8 |
|
|
|
Description: A sandwich ELISA kit for quantitative measurement of Mouse ON (Osteonectin) in samples from Serum, Plasma, Cell supernatant |
) ELISA kit for Rat ON (Osteonectin) |
|
E-EL-R0701 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 640.8 |
|
|
|
Description: A sandwich ELISA kit for quantitative measurement of Rat ON (Osteonectin) in samples from Serum, Plasma, Cell supernatant |
) CLIA kit for Human ON (Osteonectin) |
|
E-CL-H0889 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 700.8 |
|
|
|
Description: A sandwich CLIA kit for quantitative measurement of Human ON (Osteonectin) in samples from Serum, Plasma, Cell supernatant |
) CLIA kit for Mouse ON (Osteonectin) |
|
E-CL-M0530 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 700.8 |
|
|
|
Description: A sandwich CLIA kit for quantitative measurement of Mouse ON (Osteonectin) in samples from Serum, Plasma, Cell supernatant |
) CLIA kit for Rat ON (Osteonectin) |
|
E-CL-R0498 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 700.8 |
|
|
|
Description: A sandwich CLIA kit for quantitative measurement of Rat ON (Osteonectin) in samples from Serum, Plasma, Cell supernatant |
ELISA kit for Human ON (Osteonectin) |
|
ELK1682 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
|
|
|
Description: A sandwich ELISA kit for detection of Osteonectin from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
ELISA kit for Rat ON (Osteonectin) |
|
ELK1683 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
|
|
|
Description: A sandwich ELISA kit for detection of Osteonectin from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
ELISA kit for Mouse ON (Osteonectin) |
|
ELK1684 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
|
|
|
Description: A sandwich ELISA kit for detection of Osteonectin from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
) ELISA kit for Human Osteonectin (ON) |
|
KTE60336-48T |
Abbkine |
48T |
EUR 424.8 |
|
|
|
Description: Quantitative sandwich ELISA for measuring Human Osteonectin (ON) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Osteonectin (ON) |
|
KTE60336-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2702.4 |
|
|
|
Description: Quantitative sandwich ELISA for measuring Human Osteonectin (ON) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Osteonectin (ON) |
|
KTE60336-96T |
Abbkine |
96T |
EUR 686.4 |
|
|
|
Description: Quantitative sandwich ELISA for measuring Human Osteonectin (ON) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
 AffiPure Ni-NTA Agarose Bead,For His-Tagged Protein Purification |
|
N3505-010 |
GenDepot |
10ml |
EUR 380.4 |
AffiPure Ni-NTA Agarose Bead,For His-Tagged Protein Purification |
|
N3505-050 |
GenDepot |
50ml |
EUR 999.6 |
 Biotin-LC-Protein Kinase G Substrate; Biotin-LC-G-Subtide |
|
5-00802 |
CHI Scientific |
4 x 5mg |
Ask for price |
 CM Rapid Run Agarose Bead |
|
CMRR-25 |
ABTBeads |
25 ml |
EUR 122.4 |
CM Rapid Run Agarose Bead |
|
CMRR-300 |
ABTBeads |
300 ml |
EUR 590.4 |
 DEAE Rapid Run Agarose Bead |
|
DEAERR-25 |
ABTBeads |
25 ml |
EUR 122.4 |
DEAE Rapid Run Agarose Bead |
|
DEAERR-300 |
ABTBeads |
300 ml |
EUR 590.4 |
 Bead Sample Pack - 50mL Set |
|
BSP-50B2 |
Next Advance |
1pack |
EUR 484.8 |
|
Description: Bead sample pack for Bullet Blender 50mL tube models. Includes 20mL of: ZROB05, ZROB20, SSB02, SSB14B, SSB48, SSB60, SSUFO35 and SSUFO56. |
 Bead Sample Pack - 5E Set |
|
BSP-5E |
Next Advance |
1pack |
EUR 302.4 |
|
Description: Bead sample pack for Bullet Blender 5E models. Includes 10mL of: ZROB015, ZROB05, ZROB20, SSB02, SSB14B, SSB32, SSB48, SSUFO35 and SSUFO56. |
 Bead Sample Pack - 5M Set |
|
BSP-5Y |
Next Advance |
1pack |
EUR 289.2 |
|
Description: Bead sample pack for Bullet Blender 5mL Storm models. Includes 10mL of: ZROB015, ZROB05, ZROB20, SSB02, SSB14B, SSB32, SSB60, SSB110 and SSUFO35. |
 Bead Sample Pack - Full Set |
|
BSP-ALL2 |
Next Advance |
1pack |
EUR 460.8 |
|
Description: Bead sample pack inlcudes sampling of all 20 bead types in 10mL tubes. |
 Bead Sample Pack - Cell Cultures |
|
BSP-CC2 |
Next Advance |
1pack |
EUR 234 |
|
Description: Bead sample pack for homogenization of cell cultures. Includes 10mL of: GB01, GB05, ZROB015, ZROB05 and SSB02. |
 Bead Sample Pack - Microcentrifuge Set |
|
BSP-MC2 |
Next Advance |
1pack |
EUR 278.4 |
|
Description: Bead sample pack for Bullet Blender 1.5mL tube models. Includes 10mL of: ZROB015, ZROB05, ZROB10, ZROB20, SSB02, SSB14B, SSB32 and SSUFO35. |
 Bead Sample Pack - Organ Tissues |
|
BSP-OT3 |
Next Advance |
1pack |
EUR 282 |
|
Description: Bead sample pack for homogenization of organ tissues. Includes 10mL of: ZROB05, ZROB10, ZROB20, SSB14B, SSB32 and SSUFO35. |
 SP Rapid Run Agarose Bead |
|
SPRR-25 |
ABTBeads |
25 ml |
EUR 122.4 |
SP Rapid Run Agarose Bead |
|
SPRR-300 |
ABTBeads |
300 ml |
EUR 590.4 |
 ExoFACS? Kit for Serum Exosomes |
|
K1233-20 |
Biovision |
|
EUR 952.8 |
) MS-275 (Entinostat) |
|
E1KS1053 |
EnoGene |
25 mg |
EUR 296.4 |
 Methyl-PEG3-MS |
|
abx186609-250mg |
Abbexa |
250 mg |
EUR 526.8 |
|
|
 MS 245 oxalate |
|
B5540-10 |
ApexBio |
10 mg |
EUR 350.4 |
MS 245 oxalate |
|
B5540-5 |
ApexBio |
5 mg |
EUR 252 |
 Ab MS GluR1* |
|
P80000-100uL |
Pel-Freez |
100uL |
Ask for price |
 uv lamp 2x15w, 254/365nm |
|
VL215-LC |
Consort |
ea |
EUR 980.4 |
 uv lamp 2x6w, 254/365nm |
|
VL6-LC |
Consort |
ea |
EUR 645.6 |
 darkroom 254/365nm |
|
VLCN15-LC |
Consort |
ea |
EUR 1842 |
 Sulfo-NHS-LC-Biotin |
|
A8003-100 |
ApexBio |
100 mg |
EUR 170.4 |
|
Description: Sulfo-NHS-LC-biotin (Sulfosuccinimidyl 6-(biotinamido) Hexanoate) is an amine-reactive biotinylation agent. |
Sulfo-NHS-LC-Biotin |
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A8003-1000 |
ApexBio |
1 g |
EUR 686.4 |
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Description: Sulfo-NHS-LC-biotin (Sulfosuccinimidyl 6-(biotinamido) Hexanoate) is an amine-reactive biotinylation agent. |
 Complement C1R LC antibody |
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70R-49435 |
Fitzgerald |
100 ul |
EUR 292.8 |
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Description: Purified Polyclonal Complement C1R LC antibody |
 Cathepsin D LC antibody |
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70R-49618 |
Fitzgerald |
100 ul |
EUR 292.8 |
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Description: Purified Polyclonal Cathepsin D LC antibody |
Sulfo-NHS-LC-Biotin |
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2326-100 |
Biovision |
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EUR 373.2 |
Sulfo-NHS-LC-Biotin |
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2326-50 |
Biovision |
|
EUR 242.4 |
Sulfo-NHS-LC-Biotin |
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2326-set |
Biovision |
|
EUR 255.6 |
 CD224 LC Blocking Peptide |
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20-abx161054 |
Abbexa |
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 Enteropeptidase LC Blocking Peptide |
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20-abx161089 |
Abbexa |
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 MASP1 LC Blocking Peptide |
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20-abx161154 |
Abbexa |
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 Myeloperoxidase LC Blocking Peptide |
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20-abx161172 |
Abbexa |
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 Cathepsin C LC Antibody |
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20-abx121043 |
Abbexa |
-
EUR 360.00
-
EUR 526.80
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EUR 226.80
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Phosphoproteomic outcomes have been confirmed by Western blot and PBMCs’ confocal microscopy analyses. General, 38 PBMCs samples have been analyzed. A differential evaluation of PBMCs’ phosphoproteomes revealed a rise of lactotransferrin, actin-related protein 2 (ARPC2) and calgranulin-B in antibody-mediated rejection sufferers, in comparison with controls. Elevated expression of phosphorylated ARPC2 and its correlation to F-actin filaments have been confirmed in CAMR sufferers. Our outcomes are the primary proof of altered cytoskeleton group in circulating immune cells of CAMR sufferers.