Proteomic Profiling Reveals New Insights into the Allergomes of Anisakis simplex, Pseudoterranova decipiens, and Contracaecum osculatum

Anisakis simplex, Pseudoterranova decipiens, and Contracaecum osculatum third-stage larvae (L3) are fish-borne nematodes that may trigger human anisakidosis. Though A. simplex is a identified supply of allergens, information concerning the allergic potential of P. decipiens and C. osculatum is proscribed. Subsequently, we carried out comparative proteomic profiling of A. simplex, P. decipiens, and C. osculatum L3 larvae utilizing liquid chromatography-tandem mass spectrometry. In whole, 645, 397, and 261 proteins had been detected in A. simplex, P. decipiens, and C. osculatum L3 larvae, respectively.

Western blot evaluation confirmed the cross-reactivity of anti-A. simplex immunoglobulin (Ig)G antibodies with protein extracts from P. decipiens and C. osculatum L3 larvae. The recognized proteins of the Anisakidae proteomes had been characterised by label-free quantification and practical evaluation, and proteins concerned in lots of important organic mechanisms, corresponding to parasite survival, had been recognized. In C. osculatum 4, the next allergens had been recognized: Ani s 2, Ani s 5, Ani s 13, and Asc l 3.

Moreover, 28 possible allergens had been predicted in A. simplex and P. decipiens, whereas in C. osculatum, 25 potential allergens had been recognized. Among the many putative allergens, warmth shock proteins had been most often detected, adopted by paramyosin, peptidyl-prolyl cis-trans isomerase, enolase, and tropomyosin. We offer a brand new proteomic information set that could possibly be helpful for the invention of biomarkers or drug goal candidates. Moreover, our findings confirmed that along with A. simplex, P. decipiens and C. osculatum also needs to be thought-about as potential sources of allergens that might result in IgE-mediated hypersensitivity.

The Position of RodA-Conserved Cysteine Residues within the Aspergillus fumigatus Conidial Floor Group

Immune inertness of Aspergillus fumigatus conidia is attributed to its floor rodlet-layer made up of RodAp, characterised by eight conserved cysteine residues forming 4 disulfide bonds. Earlier, we confirmed that the conserved cysteine residue level (ccrp) mutations end in conidia devoid of the rodlet layer. Right here, we prolonged our research evaluating the floor group and immunoreactivity of conidia carrying ccrp-mutations with the RODA deletion mutant (∆rodA). Western blot evaluation utilizing anti-RodAp antibodies indicated the absence of RodAp within the cytoplasm of ccrpmutant conidia.

Immunolabeling revealed differential reactivity to conidial floor glucans, the ccrp-mutant conidia preferentially binding to α-(1,3)-glucan, ∆rodA conidia selectively sure to β-(1,3)-glucan; the parental pressure conidia confirmed adverse labeling. Nevertheless, permeability of ccrp-mutants and ∆rodA was much like the parental pressure conidiaProteomic analyses of the conidial floor uncovered proteins of the ccrp-mutants confirmed extra similarities with the parental pressure, however had been considerably completely different from the ∆rodA. Ccrp-mutant conidia had been much less immunostimulatory in comparison with ∆rodA conidia.

Our information counsel that (i) the conserved cysteine residues are important for the trafficking of RodAp and the group of the rodlet layer on the conidial floor, and (ii) focused level mutation could possibly be another method to check the function of fungal cell-wall genes in host-fungal interplay. Aquaporin-2 (AQP2) is a key water channel protein which determines the water permeability of the amassing duct. A number of phosphorylation websites are current on the C-terminal of AQP2 together with S256 (serine at 256 residue), S261, S264 and S/T269, that are regulated by vasopressin (VP) to modulate AQP2 trafficking.

Because the dynamics of those phosphorylations have been studied largely in rodents, little is thought concerning the phosphorylation of human AQP2 which has distinctive T269 within the place of S269 of rodent AQP2. As a result of AQP2 is excreted in urinary exosomes, the phosphoprotein profile of human AQP2 might be simply examined by means of urinary exosomes with none intervention.

Proteomic Profiling Reveals New Insights into the Allergomes of Anisakis simplex, Pseudoterranova decipiens, and Contracaecum osculatum

Steel Assisted Protein quantitation (MAPq): Multiplex evaluation of protein expression utilizing lanthanide-modified antibodies with detection by inductively coupled plasma mass spectrometry.

Understanding the advanced relationships between genomics, transcriptomics, and proteomics requires growth of extra delicate and speedy strategies of multiplexed protein evaluation. That is needed to know the connection between mobile responses to environmental stresses, illness development, and/or drug therapy; nevertheless, most strategies are restricted by low sensitivity, non-specificity, and minimal multiplexing capability. To extra totally discover the connection between a number of mobile pathways, we now have developed a novel antibody-based multiplex assay utilizing inductively coupled plasma mass spectrometry (ICP-MS), which we time period steel assisted protein quantitation (MAPq).

MAPq makes use of lanthanide-conjugated antibodies to concurrently quantify as much as 35 proteins with low pg/mL sensitivity. This methodology is very advantageous for low abundance proteins, a big limitation of many multiplex MS strategies. We noticed a restrict of detection of 0.5 pg/mL and restrict of quantitation of 5 pg/mL with nearly no background sign. We utilized this methodology to each cultured cells and mouse tissues to research modifications in low abundance nuclear and cytoplasmic proteins following drug or environmental stresses.

MAPq was discovered to be at the very least 10-times extra delicate than western blots and will detect quantitative modifications in protein expression not readily noticed utilizing standard approaches. The proteins had been confirmed by immunoblot analyses utilizing independently acquired urinary EV samples. AZGP1 specifically was discovered to be a CAMR-specific proteomic biomarker that was distinguishable from the rejection-free management group with matching kidney operate, period of transplantation, and age.

Coomassie brilliant blue G-250

20-abx082562
  • EUR 260.40
  • EUR 210.00
  • 25 g
  • 5 g

Coomassie brilliant blue G-250

CB0038 25g
EUR 90.28

Brilliant Blue FCF

HY-D0915 500mg
EUR 129.6

Coomassie Brilliant Blue G250

abx090654-5g 5 g
EUR 226.8

Coomassie Brilliant Blue R250

abx090655-5g 5 g
EUR 226.8

Coomassie Brilliant Blue Solution

GR103030 100 mL
EUR 99.6

OPTIONAL BLUE FILTER (497NM)

GDBL-BLUE 1/pk
EUR 1298.4
Description: Lab Equipment; Axygen Branded EQ

conversion screen uv/blue

VLFC26-BLUE ea
EUR 727.2

Coomassie brilliant blue R-250

20-abx082400
  • EUR 276.00
  • EUR 226.80
  • 25 g
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Coomassie brilliant blue R-250

20-abx082561
  • EUR 260.40
  • EUR 210.00
  • 25 g
  • 5 g

Brilliant Cresyl Blue (0.3%, Alcoholic)

BCA3800 1 Gal.
EUR 289.2

Brilliant Cresyl Blue (0.3%, Alcoholic)

BCA500 500 ml
EUR 108

Brilliant Cresyl Blue (0.3%, Alcoholic)

BCA999 1000 ml
EUR 139.2

Coomassie brilliant blue R-250

CB0037 5g
EUR 70.44

Coomassie Brilliant Blue R-250

CH024 10 g
EUR 145.2

Coomassie Brilliant Blue R-250

CH025 25 g
EUR 174

Coomassie Brilliant Blue R-250

CH026 50 g
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Brilliant Cresyl Blue (C.I. 51010)

GT9275-10G 10 g
EUR 103.2

Brilliant Cresyl Blue (C.I. 51010)

GT9275-25G 25 g
EUR 132

Coomassie Brilliant Blue Fast Staining Solution

abx090652-200ml 200 ml
EUR 243.6

Coomassie Brilliant Blue Gel Staining Kit

abx090653-1Kit 1 Kit
EUR 226.8

Coomassie Brilliant Blue G250 (C.I. 42655)

GT0353-100G 100 g
EUR 151.2

Coomassie Brilliant Blue G250 (C.I. 42655)

GT0353-25G 25 g
EUR 74.4

Coomassie Brilliant Blue G250 (C.I. 42655)

GT0353-5G 5 g
EUR 55.2

Coomassie Brilliant Blue R250 (C.I. 42660)

GT3543-100G 100 g
EUR 151.2

Coomassie Brilliant Blue R250 (C.I. 42660)

GT3543-25G 25 g
EUR 74.4

Coomassie Brilliant Blue R250 (C.I. 42660)

GT3543-5G 5 g
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Remazol Brilliant Blue R (C.I. 61200)

GT9632-25G 25 g
EUR 68.4

Brilliant Cresyl Blue (1.5% in 0.85% Saline)

BCS3800 1 Gal.
EUR 289.2

Brilliant Cresyl Blue (1.5% in 0.85% Saline)

BCS500 500 ml
EUR 108

Brilliant Cresyl Blue (1.5% in 0.85% Saline)

BCS999 1000 ml
EUR 139.2

Coomassie brilliant blue R-250 2 xSolution

C462151 250ml
EUR 127.86

Agarose for DNA electrophoresis

16-0027-500 500 g
EUR 410.4

Acrylamide, suitable for electrophoresis

GK5651-100G 100 g
EUR 64.8

Starch (Smithies), for electrophoresis

GE6857-1KG 1 kg
EUR 370.8

Starch (Smithies), for electrophoresis

GE6857-500G 500 g
EUR 217.2

Chiller for Electrophoresis systems

CSLCHILLER EACH
EUR 6453.54

Brilliant green

BB0242 25g
EUR 67.31

10G Coomassie Blue G-250

NAT1362 10G
EUR 133.38

BRILLIANT GREEN AGAR

B02-115-10kg 10 kg
EUR 1466.4

BRILLIANT GREEN AGAR

B02-115-2Kg 2 Kg
EUR 366

BRILLIANT GREEN AGAR

B02-115-500g 500 g
EUR 142.8

Brilliant Green Agar

MED1372 EACH
EUR 69.54

CometAssay Electrophoresis System

4250-050-ES 1 Kit
EUR 3540.96

electrophoresis power supply

EV245 ea
EUR 574.8

miniONE Electrophoresis System

ELE3400 EACH
EUR 624.72

Coomassie Blue G-250 Staining Solution

GR103035 1 L
EUR 114

ES 6 Tooth Gel Comb For ES Electrophoresis

LE1011-A4 Ea
EUR 148.8

BRILLIANT GREEN BILE AGAR

B02-122-10kg 10 kg
EUR 1520.4

BRILLIANT GREEN BILE AGAR

B02-122-2Kg 2 Kg
EUR 378

BRILLIANT GREEN BILE AGAR

B02-122-500g 500 g
EUR 146.4

Brilliant Green (C.I. 42040)

GT6123-100G 100 g
EUR 93.6

Brilliant Green (C.I. 42040)

GT6123-25G 25 g
EUR 55.2

Brilliant Crocein (C.I. 27290)

GT8393-100G 100 g
EUR 103.2

Brilliant Crocein (C.I. 27290)

GT8393-250G 250 g
EUR 180

Brilliant Crocein (C.I. 27290)

GT8393-50G 50 g
EUR 74.4

Brilliant Green Ag 500gm

228530 EACH
EUR 145.92

Brilliant Green Modified Agar

MED1160 PK10
EUR 6.84

CometAssay Electrophoresis Starter Kit

4250-050-ESK 1 Kit
EUR 3749.28

myGel Mini Electrophoresis System

BM0286 System
EUR 741.6

6X6 well Electrophoresis Apparatus

EDK626 1 UNIT
EUR 750.6

ES Horizontal Electrophoresis Set

LE1011 Set
EUR 578.4

REAL DECRETO MIX G

140-2003-G EACH
EUR 180.12

ES 8/10 Double Gel Comb For ES Electrophoresis

LE1011-A3 Ea
EUR 148.8

mPEG-PA,1K

33-MF001016-1K
  • EUR 592.80
  • EUR 237.60
  • 5G
  • G
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-PA,2K

33-MF001016-2K
  • EUR 592.80
  • EUR 237.60
  • 5G
  • G
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-NH2?HCl,2K

33-MF001050-2K
  • EUR 279.60
  • EUR 158.40
  • 5G
  • G
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SH-PEG-NH2,400

33-HE003005-400
  • EUR 1909.20
  • EUR 681.60
  • 5g
  • g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SH-PEG-NH2,500

33-HE003005-500
  • EUR 1909.20
  • EUR 681.60
  • 5g
  • g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

BRILLIANT GREEN AGAR WITH SULFAPYRIDINE

B02-117-10kg 10 kg Ask for price

BRILLIANT GREEN AGAR WITH SULFAPYRIDINE

B02-117-2kg 2kg Ask for price

BRILLIANT GREEN AGAR WITH SULFAPYRIDINE

B02-117-500g 500 g Ask for price

BRILLIANT GREEN BILE BROTH 2%

B02-118-10kg 10 kg
EUR 1226.4

BRILLIANT GREEN BILE BROTH 2%

B02-118-2Kg 2 Kg
EUR 313.2

BRILLIANT GREEN BILE BROTH 2%

B02-118-500g 500 g
EUR 128.4

Brilliant Black BN (C.I. 28440)

GT6953-100G 100 g
EUR 168

Brilliant Black BN (C.I. 28440)

GT6953-10G 10 g
EUR 64.8

Brilliant Black BN (C.I. 28440)

GT6953-25G 25 g
EUR 93.6

Cibacron Brilliant Red 3B-A

GT9393-25G 25 g
EUR 217.2

Cibacron Brilliant Red 3B-A

GT9393-5G 5 g
EUR 93.6

Blue Base for Dissecting Board

M625 1 ea.
EUR 240

Cap Insert for Cryotube Blue

390470 PK1000
EUR 21.5

Rack Blue For 30Mm Tubes

5972-0330 EACH
EUR 21.66

Blue metal tags for cryocanes

ARG1572 PK12
EUR 38.3

Rack for 100x1.5ml Microtubes Blue

CEN9382 EACH
EUR 19.38

electrophoresis ps 400v, 500ma, 50w

EV1450 ea
EUR 574.8

electrophoresis ps 400v, 500ma, 50w

EV1450-UK ea
EUR 574.8

electrophoresis ps 400v, 500ma, 50w

EV1450-US ea
EUR 574.8

electrophoresis ps 1500v, 300ma, 150w

EV2230 ea
EUR 898.8

electrophoresis ps 1500v, 300ma, 150w

EV2230-UK ea
EUR 898.8

electrophoresis ps 1500v, 300ma, 150w

EV2230-US ea
EUR 898.8

electrophoresis ps 300v, 1000ma, 150w

EV2310 ea
EUR 686.4

electrophoresis ps 300v, 1000ma, 150w

EV2310-UK ea
EUR 686.4

electrophoresis ps 300v, 1000ma, 150w

EV2310-US ea
EUR 686.4

electrophoresis ps 3000v, 150ma, 150w

EV2320 ea
EUR 898.8

electrophoresis ps 3000v, 150ma, 150w

EV2320-UK ea
EUR 898.8

electrophoresis ps 3000v, 150ma, 150w

EV2320-US ea
EUR 898.8

electrophoresis power supply uk plug

EV245-UK ea
EUR 574.8

electrophoresis power supply 120 vac

EV245-US ea
EUR 574.8

electrophoresis ps 600v, 500ma, 150w

EV2650 ea
EUR 686.4

electrophoresis ps 600v, 500ma, 150w

EV2650-UK ea
EUR 686.4

electrophoresis ps 600v, 500ma, 150w

EV2650-US ea
EUR 686.4

electrophoresis ps 300v, 2000ma, 300w

EV3020 ea
EUR 960

electrophoresis ps 300v, 2000ma, 300w

EV3020-UK ea
EUR 960

electrophoresis ps 300v, 2000ma, 300w

EV3020-US ea
EUR 960

electrophoresis ps 1200v, 500ma, 300w

EV3150 ea
EUR 960

electrophoresis ps 1200v, 500ma, 300w

EV3150-UK ea
EUR 960

electrophoresis ps 1200v, 500ma, 300w

EV3150-US ea
EUR 960

electrophoresis ps 3000v, 300ma, 300w

EV3330 ea
EUR 1456.8

electrophoresis ps 3000v, 300ma, 300w

EV3330-UK ea
EUR 1456.8

electrophoresis ps 3000v, 300ma, 300w

EV3330-US ea
EUR 1456.8

electrophoresis ps 600v, 1000ma, 300w

EV3610 ea
EUR 960

electrophoresis ps 600v, 1000ma, 300w

EV3610-UK ea
EUR 960

electrophoresis ps 600v, 1000ma, 300w

EV3610-US ea
EUR 960

electrophoresis ps 6000v, 150ma, 300w

EV3620 ea
EUR 1456.8

electrophoresis ps 6000v, 150ma, 300w

EV3620-UK ea
EUR 1456.8

electrophoresis ps 6000v, 150ma, 300w

EV3620-US ea
EUR 1456.8

5 x SDS Electrophoresis Buffer

GR103039 1 L
EUR 128.4

Styrene - Maleic Acid Copolymer 3:1 Sodium Salt - 25 g

SMA31S-G 25 grams
EUR 3751.37
Description: This product includes 25 grams of SMA Copolymer 3:1 sodium salt

Workstation for 40 Cryovials blue autoclavable

ARG1192 EACH
EUR 56.32

Capdisk for Stella Cap Light Blue

CRY1214 PK1000
EUR 50.16

Tiered rack for microtube storage blue

DD20453 EACH
EUR 12.54

Cap For UV Cuvette Micro Blue

CEL1090 PK100
EUR 32.83

Cap Disks for Microtubes - Light Blue

TUB1178 PK1000
EUR 15.96

CapLock Clip for 5.0mL tube blue

TUB2042 PK100
EUR 38.3

Screw cap for 5mL tubes Blue

TUB2134 PK200
EUR 33.63

Megarack For 10-13mm Tubes Blue

RAC3130 EACH
EUR 67.26

Megarack For 13-16mm Tubes Blue

RAC3134 EACH
EUR 67.26

ECOS Blue (XL1-Blue

FYE107-10VL 100 µl x 10 vials Ask for price

ECOS Blue (XL1-Blue

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ECOS Blue (XL1-Blue

FYE108-10VL 100 µl x 10 vials Ask for price

ECOS Blue (XL1-Blue

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ECOS Blue (XL1-Blue

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ECOS Blue (XL1-Blue

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For-Met-Ala-OH

G-1855.0250 250.0mg
EUR 224.4
Description: Sum Formula: C9H16N2O4S; CAS# [15183-28-5]

For-Met-Ala-OH

G-1855.1000 1.0g
EUR 602.4
Description: Sum Formula: C9H16N2O4S; CAS# [15183-28-5]

For-Met-Phe-OH

G-1865.0250 250.0mg
EUR 297.6
Description: Sum Formula: C15H20N2O4S; CAS# [22008-60-2]

For-Met-Phe-OH

G-1865.1000 1.0g
EUR 819.6
Description: Sum Formula: C15H20N2O4S; CAS# [22008-60-2]

For-Met-Val-OH

G-3825.0250 250.0mg
EUR 181.2
Description: Sum Formula: C11H20N2O4S; CAS# [29790-45-2]

For-Met-Val-OH

G-3825.1000 1.0g
EUR 471.6
Description: Sum Formula: C11H20N2O4S; CAS# [29790-45-2]

CometAssay Single Cell Gel Electrophoresis Assay

4250-050-K 50 tests
EUR 513.6

Electrophoresis Apparatus - 7x10cm (6-10-well)

EDK611 1 UNIT
EUR 383.11

Electrophoresis Apparatus - 7x14cm (6-10-well)

EDK613 1 UNIT
EUR 487.51

10-well protein Vertical Electrophoresis Apparatus

EDK692 1 UNIT
EUR 487.51

4 x Phosphate/SDS Electrophoresis Buffer

GR103033 1 L
EUR 139.2

Adhesion G Protein-Coupled Receptor E1 (ADGRE1) Antibody (CF-Blue)

20-abx200932
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 25 ug

Goat Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-g-48T 48T
EUR 556.8
Description: A competitive inhibition quantitative ELISA assay kit for detection of Goat Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Goat Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-g-96T 96T
EUR 721.2
Description: A competitive inhibition quantitative ELISA assay kit for detection of Goat Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Goat Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-g-48Tests 48 Tests
EUR 578.4

Goat Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-g-96Tests 96 Tests
EUR 800.4

Cryobox for cryotubes 2 mL blue colour

DD139693 EACH
EUR 19.38

Cryobox for cryotubes 2 mL blue colour

DD139729 EACH
EUR 21.66

Rigid rack blue colour for 80 microtubes

DD840516 EACH
EUR 22.8

DISPENSER BOX TOP FOR PARAFILM BLUE EA

FIL1270 EACH
EUR 55.86

Screw cap w/loop for 5ml Blue

TUB2148 PK200
EUR 33.63

Floating Rack Foam For 15ml Tubes Blue

RAC0592 PK5
EUR 39.44

Monoclonal antibody for Ankyrin G

SMC-404D 0.1mg
EUR 423.6
Description: A monoclonal antibody from clone S106-20 against Human | Rat Ankyrin G. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein 1000 C-terminal amino acids of human Ankyrin G encompassing all of Ankyrin G with the exception of Ankyrin repeats. The antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100). This MAb for Ankyrin G is not conjugated.

Monoclonal antibody for Ankyrin G

SMC-404D-A390 0.1mg
EUR 480
Description: A monoclonal antibody from clone S106-20 against Human | Rat Ankyrin G. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein 1000 C-terminal amino acids of human Ankyrin G encompassing all of Ankyrin G with the exception of Ankyrin repeats. The antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100). This MAb for Ankyrin G is conjugated with ATTO 390.

Monoclonal antibody for Ankyrin G

SMC-404D-A488 0.1mg
EUR 478.8
Description: A monoclonal antibody from clone S106-20 against Human | Rat Ankyrin G. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein 1000 C-terminal amino acids of human Ankyrin G encompassing all of Ankyrin G with the exception of Ankyrin repeats. The antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100). This MAb for Ankyrin G is conjugated with ATTO 488.

Monoclonal antibody for Ankyrin G

SMC-404D-A565 0.1mg
EUR 478.8
Description: A monoclonal antibody from clone S106-20 against Human | Rat Ankyrin G. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein 1000 C-terminal amino acids of human Ankyrin G encompassing all of Ankyrin G with the exception of Ankyrin repeats. The antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100). This MAb for Ankyrin G is conjugated with ATTO 565.

Monoclonal antibody for Ankyrin G

SMC-404D-A594 0.1mg
EUR 478.8
Description: A monoclonal antibody from clone S106-20 against Human | Rat Ankyrin G. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein 1000 C-terminal amino acids of human Ankyrin G encompassing all of Ankyrin G with the exception of Ankyrin repeats. The antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100). This MAb for Ankyrin G is conjugated with ATTO 594.

Monoclonal antibody for Ankyrin G

SMC-404D-A633 0.1mg
EUR 478.8
Description: A monoclonal antibody from clone S106-20 against Human | Rat Ankyrin G. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein 1000 C-terminal amino acids of human Ankyrin G encompassing all of Ankyrin G with the exception of Ankyrin repeats. The antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100). This MAb for Ankyrin G is conjugated with ATTO 633.

We recognized and validated six proteomic biomarkers for CAMR and clarified one CAMR-specific proteomic biomarker in KTRs. Additional scientific trials are wanted earlier than these rejection-specific biomarkers might be utilized for the early prediction, analysis, and monitoring of the scientific response of KTRs to the therapy of CAMR.

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